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Aspirin : The Side Effects
Maura Bright MBAcC, MAR, , John Morley MBAcC, MMAA, BAc, MA
Even at low doses aspirin is not harmless.

A small number of people are hypersensitive to aspirin and cannot tolerate even small amounts of the drug.

In higher doses aspirin can cause nausea, heartburn and stomach pain.

People being treated for rheumatoid arthritis who take large daily doses of aspirin are especially likely to experience gastrointestinal side effects.

Aspirin's antiplatelet activity apparently accounts for haemorrhagic strokes, caused by bleeding into the brain, in a small but significant percentage of people who use the drug regularly.

For the great majority of occasional aspirin users, internal bleeding is not a problem.

But aspirin may be unsuitable for people with uncontrolled high blood pressure, liver or kidney disease, peptic ulcer or other conditions that might increase the risk of cerebral hemorrhage or other internal bleeding.

All of today's papers (15th August 2003) warn of the risks of NSAIDs for pregnant women, following the results of a report published today in the BMJ. Researchers in California interviewed 1,000 women shortly after they became pregnant and asked them about their reproductive history and use of painkillers. They concluded that aspirin and other NSAIDs such as ibuprofen increased the risk of miscarriage by 80 per cent, while paracetamol was not a risk, regardless of how often it was used in pregnancy.

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